Wind Farm

Sandra Shefelbine


Associate Professor

Department of Mechanical & Industrial Engineering
334 Snell Engineering Center
360 Huntington Avenue
Boston, MA 02115

Office: 210A Lake Hall
Tel: 617-373-3199

Shefelbine Lab


  • PhD (2002), Mechanical Engineering, Stanford University

Research Interests

  • Multi-scale bone biomechanics – how the structure and composition of bone influences its mechanical properties
  • Mechano-adaptation of bone and joint – how tissue responds to mechanical signals

Teaching Interests

  • Solid mechanics
  • Dynamics
  • Musculoskeletal biomechanics

Honors and Awards

  • 2011 Imperial College London Rector’s Medal of Excellence in Teaching
  • 2010 Royal Academy of Engineering Exxon Mobil Teaching Award
  • 2010 Faculty of Engineering Outstanding Teaching Award
  • 2010 Department of Bioengineering student selected ‘Best Teacher’ Award
  • 2005 RCUK Academic Fellowship
  • 2002 National Science Foundation International Research Fellowship

Selected Publications

  • A. Pereira, S.J. Shefelbine (2013) The influence of load repetition in bone mechanotransduction using poroelastic finite element models: The impact of permeability. Biomechanics and Modeling in Mechanobiology (Epub ahead of print)
  • M. Vanleene, S. J. Shefelbine (2013) Therapeutic impact of low amplitude high frequency whole body vibrations on the osteogenesis imperfecta mouse bone. Bone 53(2):507-14
  • B. Poulet, T.A.T. Westerhof, R. Hamilton, S.J. Shefelbine, A.A. Pitsillides (2013) Spontaneous osteoarthritis in Str/ort mice is unlikely due to greater vulnerability to mechanical trauma. Osteoarthritis and Cartilage 21(5):756-763.
  • N. Rodriguez, M. L. Oyen, S. J. Shefelbine (2013) Insight into differences in nanoindentation properties of bone. J Mech Behavior of Biomed Mater. 18:90-99.
  • M. Doube, S.C.W. Yen, M.M. Klosowski, A.A. Farke, J.R. Hutchinson, S.J. Shefelbine (2012) Whole-bone scaling of the avian pelvic limb. J Anatomy 221(1):21-9.
  • M. Vanleene, A. Porter, P. Guillot, A. Boyde, M. Oyen, and S. J. Shefelbine (2012) Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta mice Bone 50(6):1317-23
  • S. Cheng, S. J. Shefelbine, and M. Buehler. (2012) Structural and mechanical differences between collagen homo- and heterotrimers: General insight and relevance for brittle bone disease Biophysical Journal 102(3): 640-8.