MS for Srdjan Coric Title: Parallel Beam Backprojection: An FPGA Implementation Optimized for Medical Imaging Abstract: Medical image processing in general and computerized tomography (CT) in particular can benefit greatly from hardware acceleration. This application domain is marked by computationally intensive algorithms requiring the rapid processing of large amounts of data. To date, reconfigurable hardware has not been applied to this important area. For efficient implementation and maximum speedup, fixed-point implementations are required. The associated quantization errors must be carefully balanced against the requirements of the medical community. Specifically, care must be taken so that very little error is introduced compared to floating-point implementations and the visual quality of the images is not compromised. An FPGA implementation of the parallel-beam backprojection algorithm used in CT for which all of the above requirements are met is presented in this thesis. A number of quantization issues arising in backprojection are explored with concentration on minimizing error while maximizing efficiency. The presented implementation shows significant speedup over software versions, and is more flexible than an ASIC implementation. Furthermore, this FPGA implementation can easily be adapted to medical sensors with different dynamic ranges as well as to tomographic scanners employed in a wider range of application areas including nondestructive evaluation and baggage inspection in airport terminals.