Erel Levine, Ph.D.
“Coordinated response as an organizing principle at multiple scales of Biology”
Self organization is a common thread in biology, governing the way systems are formed and behave. In this talk we will ask how biological systems, at three different scales, self-organize their response to environmental cues. To do this we will take our favorite animal, the roundworm C. elegans, and affectionately expose it to extreme heat, deprive it of food, and infect it with pathogens. We will combine quantitative measurements, theoretical considerations, and restricted modeling to study the pipeline of signal acquisition, information processing, and decision making, and to develop the concept of coordinated response.
Erel Levine got his PhD in Theoretical Physics from the Weizmann Institute of Science (2005), working with Eytan Domany and David Mukamel on collective phenomena in systems far from equilibrium. He did his postdoctoral research at the Center for Theoretical Biological Physics (at UCSD and Salk Institute), working with Terrry Hwa and Herbie Levine on experimental and theoretical models of regulatory RNAs, and with Leanne Jones on aging in the Drosophila germline. He joined the Physics Department and Center for Systems Biology at Harvard in 2010. The Levine lab is interested in developing computational, experimental and theoretical approaches to study the dynamics of acute and chronic responses to biotic and abiotic threats from the molecular scale to the organismal level, and to guide the design of synthetic biological control systems.