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s.murthy@northeastern.edu

Faculty Profile

Biography

Joined the Chemical Engineering Department in Fall 2005.

The primary focus of our research is the design of microfluidic devices for applications in clinical diagnostics and regenerative medicine. These devices are fabricated using technology originally designed for the semiconductor industry and are capable of handling and manipulating small volumes of fluids (down to tens of microliters) and small numbers of cells. Our expertise is in functionalizing microfluidic channels with a broad range of biomolecules and achieving high-resolution cell separation with these simple and easy-to-use devices.

Education

  • B.S. (Chemical Engineering) Johns Hopkins University, 1999
  • Ph.D. (Materials Science and Engineering) Massachusetts Institute of Technology, 2003
  • Postdoctoral Fellowship Harvard Medical School and Massachusetts General Hospital, 2003-2005

Research & Scholarship Interests

Microfluidic isolation of stem and progenitor cells, point-of-care diagnostics, cell surface phenomena during microfluidic flow, nanoscale probes for cell stimulation, and biopassive/bioactive coatings for neurological implants
Affiliated With

Department Research Areas

College Research Initiatives

Honors & Awards

  • 2014 COE Faculty Fellow
  • National Science Foundation CAREER Award
  • Søren Buus Outstanding Research Award

Selected Publications

  • C.H. do Prado, T. Narahari, F.H. Holland, H-N. Lee, S.K. Murthy, H.C. Brenhouse, Effects of Early Adolescent Environmental Enrichment on Cognitive Dysfunction, Prefrontal Cortex Development, and Inflammatory Cytokines After Early Life Stress, Developmental Psychobiology, 2016, 58, 482-491
  • L. Calvier,  E. Legchenko, L. Grimm, H. Sallmon, A. Hatch, B. D. Plouffe, C. Schroeder, J. Bauersachs, S. K. Murthy, G. Hansmann, Galectin-3 and Aldosterone as Potential Tandem Biomarkers in Pulmonary Arterial Hypertension, Heart, 102, 2016, 390-396 Editor’s Choice
  • D. Bavli, E. Ezra, D. Kitsberg, M. Vosk-Artzi, S.K. Murthy, Y. Nahmias, One Step Antibody-Mediated Isolation and Patterning of Multiple Cell Types in Microfluidic Devices, Biomicrofluidics,10, 2016, 024112
  • D.I. Walsh, S.K. Murthy, A. Russom, Ultra-High-Throughput Sample Preparation System for Lymphocyte Immunophenotyping Point-of-Care Diagnostics, Journal of Laboratory Automation 2016

Related News

May 1, 2018

Congratulations to all the winners of the faculty and staff awards, and to everyone for their hard work and dedication during the 2017-2018 academic school year. Faculty Fellow Guohao Dai, BioE...

April 2, 2018

ChE Professor Shashi Murthy and PhD Adam Hatch were awarded a patent for his "Methods, compositions and devices employing alginic acid hydrogels for highly specific capture and release of biological materials".

January 17, 2018

Quad Technologies, which was co-founded by ChE Professor Shashi Murthy, Sean Kevlahan (PhD ’13), Adam Hatch (PhD ’14), and Brian Plouffe (PhD ’11), was featured in BusinessWire'...

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