Wan & Muftu Receive $185K Grant
MIE associate professor Kai-tak Wan and professor Sinan Muftu have been awarded an $185K NSF grant to study Mechano-Lipidomics and Mechano-Cytosis of Drug Delivery Liposomes.
The research goal of this proposal is to build a comprehensive model of mechano-lipidomics and mechanocytosis by designing careful experiments and constructing solid-mechanics based models that are consistent with the classical understanding of membrane fusion mechanics. Nano-/micro-scale liposomes and freestanding membranes will be fabricated using common drug delivery lipids and lipid extracts from cell membrane of ovarian cancer cells.